![]() EDI-OCT was also performed to look for choroidal hyperreflective spots and measure the subfoveal choroidal thickness. Analyzed OCT parameters were stated below: volume analysis was selected to scrutinize retinal layers (number of horizontal B-scans: 23, pattern size 20° × 18°, and the distance between B-scans: 247 μm) for the detection of intraretinal hyperreflective dots, bright plaques on top of RPE-Bruch membrane complex, and outer retinal tubulations (ORTs). Heidelberg HRA2-OCT (Heidelberg retina angiograph-optical coherence tomography, Heidelberg Engineering, Heidelberg, Germany) was the SD-OCT used throughout the study. SD-OCT shows the disease progression in retinal and choroidal layers delicately in eyes with BCD and expands our knowledge about the ongoing disease process.Īdvanced disease: there is almost complete chorioretinal atrophy with occasional crystals. Choroidal hyperreflective spots were noted in 21 of 24 eyes (87.5%). Mean subfoveal choroidal thickness was 95.37 μm ± 55.93 for the study eyes (116.47 ± 46.92 μm in eyes with intermediate disease and 44.14 μm ± 42.43 in eyes with advanced disease). Mean central macular thickness was 163.08 μm ± 62.52 for all eyes (170.35 μm ± 56.46 in eyes with intermediate disease and 145.42 μm ± 77.2 in eyes with advanced disease). The remaining five eyes had advanced disease stage with very thin choroid. Choroidal hyperreflective spots were noted in 19 of 24 eyes. Appearance of bright plaque on top of RPE-Bruch membrane was present in all eyes. The remaining four eyes had advanced disease with very thin retina. ![]() Outer retinal tubulations and retinal hyperreflective dots were present in 20 of 24 eyes. Seventeen of 24 eyes were in intermediate stage of the disease and seven in advanced stage of the disease at the time of latest OCT examination performed in 2014. We analyzed the OCT features of 24 eyes of 12 patients with Bietti crystalline dystrophy (BCD) with the Heidelberg HRA2-OCT. ![]()
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